Abstract Background Immunotherapy has revolutionized the treatment of ovarian cancer (OC), but different immune microenvironments often constrain the efficacy of immunotherapeutic interventions.Therefore, there is an imperative to delineate novel immune subtypes for development of efficacious immunotherapeutic strategies.Methods The immune subtypes
BackgroundAffecting adolescent and young adults, anorexia nervosa (AN) has the highest death rate of all mental disorders.Effective treatment options are lacking and a significant proportion of patients develop severe and chronic forms of the disease with long-lasting functional impairment.Neurobiology of AN implicates the nucleus accumbens as a co
Co-infection is an underappreciated phenomenon in contemporary disease ecology despite its ubiquity and importance in nature.Viruses, and other co-infecting agents, can interact in ways that shape host and agent communities, influence infection dynamics, and drive evolutionary selective pressures.Bats are host to many viruses of zoonotic potential
The candidate mechanisms for maintaining hypertension in a chronically angiotensin II (Ang II)-infused state include direct vasoconstriction of the vasculature, disturbance of renal water/sodium handling, and central/peripheral sympathetic nerve regulation of hemodynamics.The involvement of reactive oxygen species (ROS) has been studied SOAP 3 IN 1
Health care disparities refer to differences in health and health care between groups that are closely associated with governmental, social, economic, and/or environmental policies.To address this gap in knowledge, a forum to address health disparities in different regions of the world was developed as an American Academy of Allergy, Asthma & I